Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945792 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL8945860 | 0.82 | PARP14 (0.46) | ALDH1A1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL11790054 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL11790050 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL9583160 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9583162 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11788181 | 0.75 | CTSD (0.47) | ALDH1A1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL11788092 | 0.75 | CTSD (0.47) | ALDH1A1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL5666106 | 0.69 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL31549285 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |