Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749880 | 0.78 | BRD4 (0.45) | L3MBTL1BRD4CALM1METCYP1A2 | |
| SCHEMBL64435 | 0.76 | L3MBTL1 (0.68) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL29373231 | 0.76 | L3MBTL1 (0.68) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL11330543 | 0.75 | KCNH2 (0.62) | L3MBTL1BRD4CALM1KCNH2ALDH1A1 | |
| SCHEMBL31276017 | 0.74 | L3MBTL1 (0.66) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL31236458 | 0.74 | L3MBTL1 (0.66) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL30021715 | 0.74 | L3MBTL1 (0.66) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| Bromide SCHEMBL10759788 | 0.74 | L3MBTL1 (0.66) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31087535 | 0.74 | L3MBTL1 (0.71) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL29985764 | 0.74 | L3MBTL1 (0.66) | L3MBTL1CALM1CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508400-A | Preparation of cyclic urea compounds | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-04-16 | — | — | US | disclosed |