Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2023607 | 0.89 | LMNA (0.49) | BRD4L3MBTL1POLBFEN1CYP1A2 | |
| SCHEMBL8945825 | 0.78 | L3MBTL1 (0.43) | BRD4L3MBTL1CALM1METCYP1A2 | |
| SCHEMBL64435 | 0.76 | L3MBTL1 (0.68) | L3MBTL1POLBCALM1MAOBCYP1A2 | |
| SCHEMBL29373231 | 0.76 | L3MBTL1 (0.68) | L3MBTL1POLBCALM1MAOBCYP1A2 | |
| SCHEMBL11330543 | 0.75 | KCNH2 (0.62) | BRD4L3MBTL1POLBCALM1MAOB | |
| SCHEMBL8136730 | 0.74 | L3MBTL1 (0.43) | L3MBTL1POLBCALM1MAOBMET | |
| Hydrochloric Acid SCHEMBL31087535 | 0.74 | L3MBTL1 (0.71) | L3MBTL1POLBCALM1MAOBCYP1A2 | |
| SCHEMBL31236458 | 0.74 | L3MBTL1 (0.66) | L3MBTL1POLBCALM1MAOBCYP1A2 | |
| Bromide SCHEMBL10759788 | 0.74 | L3MBTL1 (0.66) | L3MBTL1POLBCALM1MAOBCYP1A2 | |
| SCHEMBL31276017 | 0.74 | L3MBTL1 (0.66) | L3MBTL1POLBCALM1MAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762880-A1 | RETROVIRAL PROTEASE INHIBITOR COMBINATIONS | G.D. SEARLE & CO. (US) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033464-A2 | RETROVIRAL PROTEASE INHIBITOR COMBINATIONS | G.D. SEARLE & CO. (US) | 1995-12-14 | — | — | WO | claimed |