Triphenylphosphine Oxide

Triphenylphosphine Oxide

SCHEMBL8945859

O=P(c1ccccc1)(c1ccccc1)c1ccccc1.[AlH2]Cl

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
LMNA P02545 1/20 0.50
CFTR P13569 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 1/20 0.42
ALPG P10696 1/20 0.42
ALOX12 P18054 1/20 0.42
NPY1R P25929 1/20 0.42
HTT P42858 1/20 0.42
NPY2R P49146 1/20 0.42
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylphosphine Oxide SCHEMBL11470990 0.94 CA2 (0.55) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL513223 0.91 CA2 (0.58) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL3949 0.91 CA2 (0.58) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL27567935 0.88 CA2 (0.50) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL3753871 0.88 CA2 (0.55) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL9425396 0.88 CA2 (0.55) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL8431251 0.88 CA2 (0.63) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL7551485 0.88 CA2 (0.55) CA2CA4CA5ALMNACFTR
Triphenylphosphine Oxide SCHEMBL11214761 0.88 CA2 (0.55) CA2CA4CA5ALMNACFTR
SCHEMBL5439069 0.88 LMNA (0.60) CA2CA4CA5ALMNACFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5569727-A REACTING A DIEPOXIDE WITH A DIISOCYANATE IN PRESENCE OF POLYMERIZATION CATALYST WHICH IS A COMPLEX OF LEWIS ACID AND LEWIS BASE AND BAKING EUROPEAISCHE WIRTSCHAFTSGEMEINSCHAFT (LU) 1996-10-29 US claimed
CN-102731570-B Synthesis process of triphenyl alkoxyl phosphine salt WUHAN INST TECHNOLOGY 2015-05-20 CN disclosed
CN-102731570-A Synthesis process of triphenyl alkoxyl phosphine salt WUHAN INST TECHNOLOGY 2012-10-17 CN disclosed
US-5569727-A REACTING A DIEPOXIDE WITH A DIISOCYANATE IN PRESENCE OF POLYMERIZATION CATALYST WHICH IS A COMPLEX OF LEWIS ACID AND LEWIS BASE AND BAKING EUROPEAISCHE WIRTSCHAFTSGEMEINSCHAFT (LU) 1996-10-29 US disclosed