Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.73 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20235 | 0.93 | TYMS (0.85) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL9702784 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL2319488 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL1981026 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL3211535 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL767546 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL7902534 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL1636300 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL9701682 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL630093 | 0.89 | TYMS (0.79) | TYMSLPAR3LPAR2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512425-A | SMOOTHNESS, GLOSSINESS; WHITE PIGMENT IN POLYESTER FOR REFLECTION | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5474884-A | A non-photosensitive hydrophilic colloid multilayer comprising a layer of white pigment dispersing in a waterproofing polyester, a layer containing at least one color-mix inhibitor having a molecular weight of 350 or more | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| US-5445924-A | Pyrrolotriazole; high quality | FUJI PHOTO FILM CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| US-5437970-A | Reflective support having a polyester/white pigment coating and a nonphotosensitive hydrophilic colloid layer containing a dispersion of solid fine particles of a ionizable chromophore; image sharpness; antisoilants; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5397691-A | Rapid processing film and color reproduction | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-14 | — | — | US | disclosed |
| US-5395749-A | Support with sulfone, sulfide or sulfoxide compound in layer | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5378594-A | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| US-5356763-A | Rapid processing, light fastness, quality images; magenta couplers, anticolor mixing agents | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| US-5342742-A | Silver halide color photographic light-sensitive material comprising a pyrrolotriazole cyan coupler and a specific yellow coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| US-5300419-A | With ureido-cyan coupler and hydrzino stabilizer; colorfastness | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5284745-A | Ripening, chemical sensitization under limited pH; rapid processing, latent-image stability, high contrast and sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5278039-A | Nonfading silver halide photographic material with layers of yellow couplers and aromatic amines | FUJI PHOTO FILM CO., LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5264331-A | Phenylenediamine developers for silver halide emulsion images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5200310-A | Rapid processing, high sensitivity, good in safelight aptitude, wear resistance, pressure resistance | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |