Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | STAT5B | P51692 | 2/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346204 | 0.87 | CYP3A4 (0.42) | CA1CA2POLBKEAP1NFE2L2 | |
| SCHEMBL8055654 | 0.84 | POLB (0.43) | CA1CA2POLBKEAP1NFE2L2 | |
| SCHEMBL8879054 | 0.80 | STAT5B (0.45) | F2STAT5BNR1D1STAT3POLB | |
| SCHEMBL9181881 | 0.77 | STAT5B (0.45) | F2STAT5BNR1D1STAT3CA2 | |
| SCHEMBL9178323 | 0.76 | STAT5B (0.44) | F2STAT5BNR1D1STAT3POLB | |
| SCHEMBL5708145 | 0.76 | C5AR1 (0.49) | F2STAT5BNR1D1STAT3KEAP1 | |
| SCHEMBL2960697 | 0.74 | AGER (0.45) | F2STAT5BNR1D1POLBKEAP1 | |
| SCHEMBL7067656 | 0.74 | STAT5B (0.44) | F2STAT5BNR1D1STAT3CA1 | |
| SCHEMBL5011784 | 0.73 | CYP1A2 (0.40) | CA1CA2POLBMAPTLMNA | |
| SCHEMBL14327847 | 0.73 | STAT5B (0.49) | F2STAT5BSTAT3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602377-B1 | Polymers containing N,N-disubstituted sulfonamide side groups and their use in radiation-sensitive compositions | HOECHST AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| US-5529886-A | PHOTOSENSITIVE MIXTURE OF A COMPOUND WHICH ON EXPOSURE TO ACTINIC RADIATION FORMS ACID, AND AN ACID-CLEAVABLE ACRYLATE HOMO OR COPOLYMER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5442087-A | Preparing offset printing plates and photoresists | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |
| EP-0602377-A1 | Polymers containing N,N-disubstituted sulfonamide side groups and their use in radiation-sensitive compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |