SCHEMBL7067656

SCHEMBL7067656

Cc1ccc(S(=O)(=O)N(CCc2ccc(N)cc2)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 2/20 0.44
CNR2 P34972 4/20 0.44
ADRB3 P13945 1/20 0.41
STAT3 P40763 1/20 0.41
F2 P00734 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA9 Q16790 2/20 0.39
TP53 P04637 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.39
PTPN1 P18031 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
NR1D1 P20393 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6926342 0.87 CA1 (0.45) STAT5BCNR2STAT3F2CA12
SCHEMBL6802678 0.85 BMP1 (0.46) STAT5BCNR2CA12CA1CA2
SCHEMBL6796826 0.84 PTPRB (0.45) STAT5BCNR2ADRB3TP53MEN1
SCHEMBL7063146 0.84 STAT5B (0.47) STAT5BCNR2CA12CA1CA2
SCHEMBL22516852 0.82 PHLPP2 (0.40) STAT5BADRB3F2CA12CA1
SCHEMBL6807428 0.81 PTGER2 (0.41) STAT5BADRB3F2CA12CA1
SCHEMBL14327847 0.81 STAT5B (0.49) STAT5BCNR2STAT3F2CA12
SCHEMBL6804073 0.81 CNR2 (0.48) CNR2TP53TAS2R14PTPN1POLB
SCHEMBL14327849 0.80 STAT5B (0.48) STAT5BCNR2STAT3F2CA12
SCHEMBL6803115 0.80 KCNA5 (0.41) ADRB3TAS2R14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed