Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858294 | 0.79 | KMT2A (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2THRB | |
| SCHEMBL8752627 | 0.77 | KMT2A (0.56) | ALDH1A1KMT2AMEN1POLBRAB9A | |
| SCHEMBL3275099 | 0.73 | ALDH1A1 (0.56) | ELANEALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL1856286 | 0.73 | KMT2A (0.40) | KMT2AMEN1POLBF2MMP13 | |
| SCHEMBL1232411 | 0.72 | PKM (0.67) | ELANEALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL5316222 | 0.72 | KMT2A (0.74) | ELANEALDH1A1KMT2AMEN1POLB | |
| SCHEMBL1859337 | 0.72 | ESR1 (0.39) | KMT2AMEN1POLBNPSR1F2 | |
| SCHEMBL31220432 | 0.72 | HSP90AA1 (0.54) | ALDH1A1KMT2AMAPTTP53F2 | |
| SCHEMBL9915684 | 0.72 | ELANE (0.64) | ELANEALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL172511 | 0.72 | ELANE (0.64) | ELANEALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602377-B1 | Polymers containing N,N-disubstituted sulfonamide side groups and their use in radiation-sensitive compositions | HOECHST AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| US-5529886-A | PHOTOSENSITIVE MIXTURE OF A COMPOUND WHICH ON EXPOSURE TO ACTINIC RADIATION FORMS ACID, AND AN ACID-CLEAVABLE ACRYLATE HOMO OR COPOLYMER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5442087-A | Preparing offset printing plates and photoresists | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |
| EP-0602377-A1 | Polymers containing N,N-disubstituted sulfonamide side groups and their use in radiation-sensitive compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |