SCHEMBL8946160

SCHEMBL8946160

C/C=C/C1CCC(c2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)cc2F)CO1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 6/20 0.33
NAAA Q02083 1/20 0.32
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18718461 0.96 FPR2 (0.36) FPR2NAAAFGFR1FGFR2GRIN1
SCHEMBL12023985 0.95 FPR2 (0.35) FPR2NAAAFGFR1FGFR2GRIN1
SCHEMBL8946117 0.94 FPR2 (0.35) FPR2
SCHEMBL8946026 0.93 RARA (0.32) FPR2
SCHEMBL13000181 0.93
SCHEMBL8946045 0.92 FPR2 (0.34) FPR2
SCHEMBL8946205 0.91 FPR2 (0.33) FPR2
SCHEMBL8946158 0.91 FPR2 (0.33) FPR2
SCHEMBL8946050 0.91 FPR2 (0.33) FPR2
SCHEMBL8945989 0.91 FPR2 (0.33) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed