Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605597 | 0.87 | SIGMAR1 (0.76) | SIGMAR1MAPTUSP2ALDH1A1KDM4E | |
| SCHEMBL30718981 | 0.85 | SIGMAR1 (0.66) | SIGMAR1MAPTUSP2ALDH1A1KDM4E | |
| SCHEMBL7305898 | 0.80 | SIGMAR1 (0.77) | SIGMAR1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL7299921 | 0.79 | SIGMAR1 (1.00) | SIGMAR1USP2ALDH1A1KDM4ETSHR | |
| SCHEMBL7294524 | 0.79 | SIGMAR1 (0.76) | SIGMAR1MAPTALDH1A1KDM4EHTR2B | |
| SCHEMBL3396548 | 0.79 | SIGMAR1 (0.67) | SIGMAR1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL17237763 | 0.79 | SIGMAR1 (0.75) | SIGMAR1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL7298240 | 0.79 | SIGMAR1 (0.75) | SIGMAR1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL7299989 | 0.79 | SIGMAR1 (0.75) | SIGMAR1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL14786700 | 0.78 | SIGMAR1 (0.66) | SIGMAR1MAPTALDH1A1KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |