Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.75 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299921 | 0.86 | SIGMAR1 (1.00) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL8946184 | 0.83 | SIGMAR1 (0.65) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL7294524 | 0.83 | SIGMAR1 (0.76) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL14786700 | 0.82 | SIGMAR1 (0.66) | SIGMAR1HTR1ADRD2ALDH1A1 | |
| SCHEMBL7305898 | 0.82 | SIGMAR1 (0.77) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL7297159 | 0.81 | SIGMAR1 (0.81) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL7299375 | 0.81 | SIGMAR1 (0.69) | SIGMAR1HTR2BHTR1ADRD2MEN1 | |
| SCHEMBL466945 | 0.81 | SIGMAR1 (0.76) | SIGMAR1ACHEHTR2BHTR1AMAOB | |
| SCHEMBL7293937 | 0.81 | SIGMAR1 (0.67) | SIGMAR1ACHEHTR2BHTR1APPARG | |
| SCHEMBL8946214 | 0.81 | SIGMAR1 (0.67) | SIGMAR1ACHEHTR2BHTR1APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |