Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775101 | 0.85 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL9258827 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL9258832 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL28156337 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| Bicarbonate SCHEMBL10810371 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EPDE10A | |
| SCHEMBL3067398 | 0.78 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL28977964 | 0.77 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTKDM4ELMNA | |
| SCHEMBL29860539 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL351486 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E | |
| SCHEMBL8645930 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTDYRK1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493027-A | ANTIEPILEPTIC AGENTS, NEUROGENATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1994017042-A1 | ANTICONVULSIVE AGENTS AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-08-04 | — | — | WO | disclosed |
| EP-0239992-A1 | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4689423-A | Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |