Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946373 | 1.00 | MAOA (0.34) | MAOAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8946380 | 1.00 | MAOA (0.34) | MAOAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8946476 | 0.77 | S100B (0.34) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL8946488 | 0.77 | S100B (0.34) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL8946484 | 0.77 | S100B (0.34) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL8946478 | 0.69 | MAPT (0.35) | MAOAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8946486 | 0.69 | MAPT (0.35) | MAOAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8946494 | 0.69 | MAPT (0.35) | MAOAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8946317 | 0.68 | — | — | |
| SCHEMBL8946316 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |