Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459937 | 0.87 | FABP3 (0.52) | KMT2AKDM4EDPP4DHODHALDH1A1 | |
| SCHEMBL8946850 | 0.85 | KDM4E (0.62) | KMT2AKDM4ETSHRALDH1A1GAA | |
| SCHEMBL4395939 | 0.80 | KDM4E (0.65) | KMT2AL3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL10377531 | 0.77 | KDM4E (0.51) | KMT2AKDM4EDHODHTSHRALDH1A1 | |
| SCHEMBL10475598 | 0.76 | DHODH (0.52) | KMT2AKDM4EDPP4DHODHTSHR | |
| SCHEMBL4460195 | 0.75 | PLA2G2A (0.53) | KMT2AKDM4EDPP4TSHRALDH1A1 | |
| SCHEMBL8946710 | 0.74 | HTT (0.47) | KMT2AL3MBTL1DPP4TSHRALDH1A1 | |
| SCHEMBL8946509 | 0.73 | L3MBTL1 (0.60) | KMT2AL3MBTL1KDM4EDPP4ALDH1A1 | |
| SCHEMBL10375294 | 0.73 | KMT2A (0.48) | KMT2AL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL8946825 | 0.72 | DHODH (0.41) | KMT2AL3MBTL1DPP4DHODHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |