Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946432 | 1.00 | KMT2A (0.33) | KMT2AADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL8946427 | 1.00 | KMT2A (0.33) | KMT2AADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL8946400 | 0.84 | BACE1 (0.34) | — | |
| SCHEMBL8946395 | 0.84 | BACE1 (0.34) | — | |
| SCHEMBL8946403 | 0.84 | BACE1 (0.34) | — | |
| SCHEMBL8946842 | 0.81 | S100B (0.35) | — | |
| SCHEMBL8946828 | 0.81 | S100B (0.35) | — | |
| SCHEMBL8946834 | 0.81 | S100B (0.35) | — | |
| SCHEMBL8946532 | 0.78 | CYP1A2 (0.33) | ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL8946527 | 0.78 | CYP1A2 (0.33) | ADRA2AADRA2BADRA2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | claimed |
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |