Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946532 | 1.00 | CYP1A2 (0.33) | CYP1A2POLBCYP3A4CYP2C19KDM4E | |
| SCHEMBL8946536 | 1.00 | CYP1A2 (0.33) | CYP1A2POLBCYP3A4CYP2C19KDM4E | |
| SCHEMBL8946453 | 0.84 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CADRA1BGAA | |
| SCHEMBL8946458 | 0.84 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CADRA1BGAA | |
| SCHEMBL8946404 | 0.84 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CADRA1BGAA | |
| SCHEMBL8946424 | 0.82 | HPGD (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8946411 | 0.82 | HPGD (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8946416 | 0.82 | HPGD (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8946427 | 0.78 | KMT2A (0.33) | ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL8946439 | 0.78 | KMT2A (0.33) | ADRA2AADRA2BADRA2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | claimed |
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |