Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 10/20 | 0.56 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946725 | 0.94 | NTRK1 (0.50) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946571 | 0.91 | LPAR1 (0.50) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946564 | 0.90 | NTRK1 (0.48) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946618 | 0.89 | L3MBTL1 (0.51) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946473 | 0.89 | NTRK1 (0.45) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946757 | 0.88 | NTRK1 (0.48) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946752 | 0.88 | LPAR1 (0.59) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946460 | 0.87 | NTRK1 (0.43) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946762 | 0.87 | NTRK1 (0.45) | NTRK1NTRK3LPAR1KMT2ALMNA | |
| SCHEMBL8946456 | 0.86 | LPAR1 (0.50) | NTRK1LPAR1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |