Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946725 | 0.91 | NTRK1 (0.50) | LPAR1NTRK1NTRK3LMNAKMT2A | |
| SCHEMBL8946455 | 0.91 | NTRK1 (0.56) | LPAR1NTRK1NTRK3LMNAKMT2A | |
| SCHEMBL8946456 | 0.89 | LPAR1 (0.50) | LPAR1NTRK1LMNAKMT2ACYP1A2 | |
| SCHEMBL8946618 | 0.87 | L3MBTL1 (0.51) | LPAR1NTRK1NTRK3LMNAKMT2A | |
| SCHEMBL8946498 | 0.85 | NTRK1 (0.47) | NTRK1NTRK3LMNAKMT2ACYP1A2 | |
| SCHEMBL8946655 | 0.84 | LPAR1 (0.46) | LPAR1NTRK1LMNAKMT2A | |
| SCHEMBL8946564 | 0.84 | NTRK1 (0.48) | LPAR1NTRK1NTRK3LMNAKMT2A | |
| SCHEMBL8946473 | 0.83 | NTRK1 (0.45) | LPAR1NTRK1NTRK3LMNAKMT2A | |
| SCHEMBL8946420 | 0.82 | L3MBTL1 (0.47) | LPAR1NTRK1NTRK3 | |
| SCHEMBL8946757 | 0.81 | NTRK1 (0.48) | LPAR1NTRK1NTRK3LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |