Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946713 | 0.91 | L3MBTL1 (0.41) | L3MBTL1NTRK1CNR1 | |
| SCHEMBL8946441 | 0.89 | NTRK1 (0.48) | NTRK1NTRK3LMNAALDH1A1MAPK1 | |
| SCHEMBL8946563 | 0.88 | NTRK1 (0.57) | NTRK1NTRK3LMNACYP1A2CYP2C9 | |
| SCHEMBL8946567 | 0.88 | NTRK1 (0.45) | L3MBTL1NTRK1NTRK3LMNACYP1A2 | |
| SCHEMBL8946617 | 0.88 | L3MBTL1 (0.53) | L3MBTL1NTRK1NTRK3NTRK2 | |
| SCHEMBL8946363 | 0.87 | NTRK1 (0.51) | NTRK1NTRK3LMNACYP1A2CYP2C9 | |
| SCHEMBL8946926 | 0.86 | NTRK1 (0.53) | NTRK1NTRK3KMT2ANTRK2 | |
| SCHEMBL8946671 | 0.86 | NTRK1 (0.48) | NTRK1NTRK3LMNAALDH1A1MAPK1 | |
| SCHEMBL8946624 | 0.86 | NTRK1 (0.43) | NTRK1NTRK3LMNACYP1A2ALDH1A1 | |
| SCHEMBL8946498 | 0.86 | NTRK1 (0.47) | NTRK1NTRK3LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |