Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 7/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946363 | 0.91 | NTRK1 (0.51) | NTRK1ADORA1NTRK3CYP2C9CYP1A2 | |
| SCHEMBL8946563 | 0.90 | NTRK1 (0.57) | NTRK1NTRK3CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8946576 | 0.86 | L3MBTL1 (0.51) | NTRK1NTRK3CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8946571 | 0.85 | LPAR1 (0.50) | NTRK1ADORA1NTRK3CYP2C9CYP1A2 | |
| SCHEMBL8946713 | 0.83 | L3MBTL1 (0.41) | NTRK1ADORA1 | |
| SCHEMBL8946441 | 0.82 | NTRK1 (0.48) | NTRK1NTRK3MAPK14LMNAMEN1 | |
| SCHEMBL8946567 | 0.82 | NTRK1 (0.45) | NTRK1NTRK3CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8946624 | 0.80 | NTRK1 (0.43) | NTRK1NTRK3CYP1A2LMNAMAPT | |
| SCHEMBL8946671 | 0.80 | NTRK1 (0.48) | NTRK1NTRK3LMNAMEN1MAPT | |
| SCHEMBL8946682 | 0.79 | NTRK1 (0.45) | NTRK1NTRK3CYP2C9LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |