Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.50 |
| ▸ | CA2 | P00918 | 13/20 | 0.50 |
| ▸ | CA4 | P22748 | 13/20 | 0.50 |
| ▸ | CA6 | P23280 | 13/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531330 | 0.83 | CA1 (0.49) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946637 | 0.79 | CA1 (0.54) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9528233 | 0.78 | ALDH1A1 (0.32) | CA1CA2CA4CA6 | |
| SCHEMBL9527328 | 0.78 | CA1 (0.50) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946893 | 0.75 | CA1 (0.52) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL10381644 | 0.74 | CA1 (0.41) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9526921 | 0.72 | CA1 (0.46) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9527581 | 0.72 | CA1 (0.46) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946616 | 0.69 | CA1 (0.56) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9528165 | 0.69 | CA1 (0.57) | CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |