Ethylene Glycol

Ethylene Glycol

SCHEMBL8946650

CCOCCOCC(=O)O.OCCO

nearest known ligand 0.50

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.46
THRB P10828 2/20 0.41
GLA P06280 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EPHX2 P34913 1/20 0.36
PTGS1 P23219 1/20 0.35
CTH P32929 1/20 0.33
CBS P35520 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
CES2 O00748 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2C19 P33261 1/20 0.32
PAM P19021 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL8984224 0.98 ALDH1A1 (0.48) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL1172675 0.93 ALDH1A1 (0.52) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL29525974 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL6275021 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL22609510 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL2865428 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL19066801 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
SCHEMBL1056083 0.91 ALDH1A1 (0.50) ALDH1A1TSHRTHRBGLAL3MBTL1
Ethylene Glycol SCHEMBL3728790 0.88 ALDH1A1 (0.43) ALDH1A1TSHRTHRBGLAL3MBTL1
Ethylene Glycol SCHEMBL7122296 0.88 TSHR (0.41) TSHRTHRBEPHX2PTGS1CTH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545349-A Bleaching composition KAO CORPORATION (JP) 1996-08-13 US disclosed
EP-0447553-B1 BLEACHING COMPOSITION KAO CORP (JP) 1996-06-12 EP disclosed