SCHEMBL894682

SCHEMBL894682

NC(=O)c1cc(N)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.69
HSD17B10 Q99714 4/20 0.69
ALDH1A1 P00352 3/20 0.69
MEN1 O00255 3/20 0.69
THRB P10828 3/20 0.69
KMT2A Q03164 3/20 0.69
TDP1 Q9NUW8 3/20 0.69
ALOX15 P16050 3/20 0.69
CYP3A4 P08684 3/20 0.69
HPGD P15428 2/20 0.69
RECQL P46063 2/20 0.69
CASP1 P29466 2/20 0.69
KDR P35968 2/20 0.69
TNF P01375 1/20 0.69
HSPD1 P10809 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
PTGS2 P35354 1/20 0.69
BRCA1 P38398 1/20 0.69
CASP7 P55210 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesalamine SCHEMBL1967328 0.82 KDM4E (1.00) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL28077836 0.82 KDM4E (1.00) KDM4EHSD17B10ALDH1A1MEN1THRB
SCHEMBL1526264 0.82 MAPT (0.69) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL29354798 0.82 KDM4E (1.00) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL31297 0.82 KDM4E (1.00) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL7632741 0.82 KDM4E (0.73) KDM4EHSD17B10ALDH1A1MEN1THRB
SCHEMBL1803658 0.81 MAPT (0.53) KDM4EHSD17B10ALDH1A1MEN1THRB
SCHEMBL22630592 0.81 KDM4E (0.62) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL9688231 0.80 KDM4E (0.96) KDM4EHSD17B10ALDH1A1MEN1THRB
Mesalamine SCHEMBL15329203 0.80 KDM4E (0.96) KDM4EHSD17B10ALDH1A1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113347969-A Composition for eliminating senescent cells 维也纳自然资源与生命科学大学 2021-09-03 CN claimed
EP-0345728-B1 Dye composition for keratinous fiber KAO CORP (JP) 1994-09-14 EP claimed
US-5047066-A Dye composition for keratinous fibers containing a 2-substituted 4-aminophenol compound as a developer, and a coupling substance KAO CORPORATION (JP) 1991-09-10 US claimed
EP-0345728-A2 Dye composition for keratinous fiber Kao Corporation (JP) 1989-12-13 EP claimed
CN-113347969-A Composition for eliminating senescent cells 维也纳自然资源与生命科学大学 2021-09-03 CN disclosed
US-9872822-B2 Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition L'OREAL (FR) 2018-01-23 US disclosed
US-9872822-B2 Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition L'OREAL (FR) 2018-01-23 US disclosed
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed
EP-2440034-A1 HIGH OIL CONTENT PLANTS Bayer BioScience N.V. (BE) 2012-04-18 EP disclosed
US-20120084883-A1 High Oil Content Plants BAYER CROPSCIENCE N.V. (BE) 2012-04-05 US disclosed
WO-2010142424-A1 HIGH OIL CONTENT PLANTS BAYER BIOSCIENCE N.V. (BE) 2010-12-16 WO disclosed
US-5668258-A Phenylboronic acid complexing reagents derived from aminosalicylcic acid PROLINX, INC. (US) 1997-09-16 US disclosed
US-5648470-A Phenylboronic acid complexing reagents derived from aminosalicyclic acid PROLINX, INC. (US) 1997-07-15 US disclosed
US-5594151-A Phenylboronic acid complexing reagents derived from aminosalicylic acid PROLINX, INC. (US) 1997-01-14 US disclosed
EP-0741734-A1 PHENYLBORONIC ACID COMPLEXES PROLINX, INC. (US) 1996-11-13 EP disclosed
WO-1995020591-A1 PHENYLBORONIC ACID COMPLEXES PROLINX, INC. (US) 1995-08-03 WO disclosed
EP-0345728-B1 Dye composition for keratinous fiber KAO CORP (JP) 1994-09-14 EP disclosed
US-5047066-A Dye composition for keratinous fibers containing a 2-substituted 4-aminophenol compound as a developer, and a coupling substance KAO CORPORATION (JP) 1991-09-10 US disclosed
EP-0345728-A2 Dye composition for keratinous fiber Kao Corporation (JP) 1989-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION KRT18, ARSA, SQOR KDM4E 1417/4885HSD17B10 529/4885ALDH1A1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.