Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555456 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL19838475 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL31744504 | 0.74 | GRIN2D (0.60) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL4393644 | 0.71 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL2858051 | 0.68 | MTNR1A (0.62) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL6669729 | 0.67 | EGFR (0.63) | LMNAKDM4EALDH1A1HTTGAA | |
| SCHEMBL4256786 | 0.67 | GRIN2D (0.60) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL31609245 | 0.67 | GRIN2D (0.60) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL7086829 | 0.67 | NPSR1 (0.59) | MTNR1AMTNR1BLMNAL3MBTL1GRIN2D | |
| SCHEMBL4293204 | 0.65 | HTR2A (0.47) | HTR2AHTR2CTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552428-A | ANTIARRHYTHMIA AGENTS FOR CARDIOVASCULAR DISORDERS USING MELATONIN DERIVATIVES | INSTITUTO FARMACOLOGICO LOMBARDO-IFLO, S.A.S. (IT) | 1996-09-03 | — | — | US | disclosed |