Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901037 | 1.00 | TSHR (0.41) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL20819805 | 0.85 | TSHR (0.46) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL20819807 | 0.84 | MEN1 (0.36) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL5710506 | 0.79 | TDP1 (0.37) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL2144022 | 0.79 | TSHR (0.40) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL465993 | 0.78 | TSHR (0.40) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL1024005 | 0.78 | TSHR (0.40) | TSHRCYP3A4TDP1PKMSMN1; SMN2 | |
| SCHEMBL222774 | 0.77 | ALDH1A1 (0.46) | TSHRTDP1PKMMAPTALDH1A1 | |
| SCHEMBL126032 | 0.77 | ALDH1A1 (0.46) | TSHRTDP1PKMMAPTALDH1A1 | |
| SCHEMBL3762398 | 0.77 | HPGD (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587244-A | Low pressure medical silicone gasket | DR. DAVID E. FLINCHBAUGH | 1996-12-24 | — | — | US | disclosed |
| US-5179134-A | Acryloyloxysilyl compound with a silicone and a photoinitiator for sealants, coatings and potting material which are curable | LOCTITE CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |