SCHEMBL8947045

SCHEMBL8947045

CN1C2CCC1CC(C(=O)O)C2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
CYP2C9 P11712 2/20 0.52
TDP1 Q9NUW8 2/20 0.48
HTR3E A5X5Y0 2/20 0.43
HTR3B O95264 2/20 0.43
HTR3A P46098 2/20 0.43
HTR3D Q70Z44 2/20 0.43
HTR3C Q8WXA8 2/20 0.43
CHRNA7 P36544 1/20 0.43
CHRM3 P20309 5/20 0.41
CHRM2 P08172 3/20 0.41
CHRM1 P11229 3/20 0.41
CHRM4 P08173 2/20 0.41
CHRM5 P08912 2/20 0.41
CYP2D6 P10635 2/20 0.40
HSD17B10 Q99714 1/20 0.40
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11388564 1.00 LMNA (0.52) LMNACYP2C9TDP1HTR3EHTR3B
Hydrochloric Acid SCHEMBL2417970 0.98 TDP1 (0.52) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL7662681 0.82 LMNA (0.48) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL7662691 0.82 LMNA (0.48) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL7662685 0.82 LMNA (0.48) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL6648506 0.81 LMNA (0.52) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL23475160 0.80 MAPT (0.40) LMNACYP2C9TDP1MEN1KMT2A
SCHEMBL26728043 0.80 MAPT (0.40) LMNACYP2C9TDP1MEN1KMT2A
SCHEMBL4128527 0.79 LMNA (0.50) LMNACYP2C9TDP1HTR3EHTR3B
SCHEMBL16891684 0.77 SMN1; SMN2 (0.39) LMNATDP1CHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20220362160-A1 ABUSE RESISTANT CAPSULE R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-11-17 US claimed
US-11464747-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20250345767-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-11-13 US disclosed
EP-3824878-B1 ABUSE RESISTANT CAPSULE SCHERER TECHNOLOGIES LLC R P (US) 2025-11-12 EP disclosed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US disclosed
US-20240108726-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT ACURA PHARMACEUTICALS, INC. (US) 2024-04-04 US disclosed
US-11857629-B2 Methods and compositions for self-regulated release of active pharmaceutical ingredient ACURA PHARMACEUTICALS, INC. (US) 2024-01-02 US disclosed
US-20230390210-A1 MODIFIED RELEASE SOFTGEL CAPSULES R.P. SCHERER TECHNOLOGIES, LLC 2023-12-07 US disclosed
US-20230372252-A1 CONTROLLED RELEASE FILL COMPOSITIONS AND CAPSULES CONTAINING SAME R.P. SCHERER TECHNOLOGIES, LLC (US) 2023-11-23 US disclosed
US-20230330044-A1 METHODS AND COMPOSITIONS FOR INTERFERING WITH EXTRACTION OR CONVERSION OF A DRUG SUSCEPTIBLE TO ABUSE ACURA PHARMACEUTICALS INC (US) 2023-10-19 US disclosed
WO-2014085599-A1 SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT ACURA PHARMACEUTICALS, INC. (US) 2014-06-05 WO disclosed
WO-2013025425-A1 SOLUBLE GUANYLATE CYCLASE ACTIVATORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-21 WO disclosed
CN-101027044-A Oral dosage form safeguarded against abuse GRUENENTHAL GMBH (DE) 2007-08-29 CN disclosed
US-5561149-A FOR NASAL ADMINISTRATION SANDOZ LTD. (CH) 1996-10-01 US disclosed
US-4281130-A Lower-alkyl 4,6,7,8,8a-9-hexahydro-6,9-ethanothieno[3,2-f]indolizine-10-carboxylate STERLING DRUG INC. (US) 1981-07-28 US disclosed
US-4233448-A 3-Methoxycarbonyl-2-(2-thienyl)-8-azabicyclo[3.2.1]octane-8-acetamide and salts thereof STERLING DRUG INC. (US) 1980-11-11 US disclosed
US-4233449-A 1-(8-Methyl-2-phenyl(or thienyl)-8-azabicyclo[3.2.1]octan-3-yl) ethanone STERLING DRUG INC. (US) 1980-11-11 US disclosed
US-4214084-A Ethanopyrrolo[1,2-b]isoquinolines STERLING DRUG INC. (US) 1980-07-22 US disclosed
US-4179567-A 2-Aryltropane compounds STERLING DRUG INC. (US) 1979-12-18 US disclosed