Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.40 |
| ▸ | HTR3B | O95264 | 3/20 | 0.40 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514959 | 0.91 | CHRM3 (0.43) | LMNACYP2C9SMN1; SMN2CHRM3CYP2D6 | |
| SCHEMBL21145976 | 0.81 | SMN1; SMN2 (0.37) | LMNACYP2C9SMN1; SMN2CHRM3OPRK1 | |
| SCHEMBL31008717 | 0.79 | SMN1; SMN2 (0.36) | LMNACYP2C9SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8947045 | 0.79 | LMNA (0.52) | LMNACYP2C9SMN1; SMN2CHRM3HTR3E | |
| SCHEMBL11388564 | 0.79 | LMNA (0.52) | LMNACYP2C9SMN1; SMN2CHRM3HTR3E | |
| SCHEMBL6648506 | 0.79 | LMNA (0.52) | LMNACYP2C9CHRM3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL2417970 | 0.77 | TDP1 (0.52) | LMNACYP2C9SMN1; SMN2CHRM3HTR3E | |
| SCHEMBL7662691 | 0.76 | LMNA (0.48) | LMNACYP2C9SMN1; SMN2CHRM3HTR3E | |
| SCHEMBL7662685 | 0.76 | LMNA (0.48) | LMNACYP2C9SMN1; SMN2CHRM3HTR3E | |
| Hydrochloric Acid SCHEMBL9045619 | 0.76 | LMNA (0.48) | LMNACYP2C9CHRM3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117869-B2 | Compounds, compositions and methods for treatment of myopia | AERIE PHARMACEUTICALS, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200247760-A1 | Compounds, Compositions and Methods for Treatment of Myopia | ALCON INC. (CH) | 2020-08-06 | — | — | US | disclosed |
| EP-2989099-A1 | A PROCESS FOR THE SYNTHESIS OF MARAVIROC | Zentiva K.S. (CZ) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014173375-A1 | A PROCESS FOR THE SYNTHESIS OF MARAVIROC | ZENTIVA, K.S. (CZ) | 2014-10-30 | — | — | WO | disclosed |
| US-20090093468-A1 | Peptide Deformylase Inhibitors | ARPIDA A/S (DK) | 2009-04-09 | — | — | US | disclosed |
| US-5070094-A | ANTIARRHYTHMIA AGENTS; PROLONGING CARDIAC ACTION POTENTIAL REP OLARIZATION | G. D. SEARLE & CO. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0416521-A1 | N-Benzyltropaneamides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117869-B2 | Compounds, compositions and methods for treatment of myopia | MYOC, HDAC8, PDE6C | LMNA 134/4885CYP2C9 4296/4885SMN1; SMN2 1696/4885 |
| US-20090093468-A1 | Peptide Deformylase Inhibitors | PDF, PEPD, MRPL21 | LMNA 2707/4885CYP2C9 4152/4885SMN1; SMN2 2599/4885 |
| US-20200247760-A1 | Compounds, Compositions and Methods for Treatment of Myopia | MYOC, HDAC8, PDE6C | LMNA 134/4885CYP2C9 4296/4885SMN1; SMN2 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.