SCHEMBL8947127

SCHEMBL8947127

CCOP(=O)(OCC)C(COC(CCc1ccccc1)CS(=O)(=O)O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.43
POLB P06746 1/20 0.43
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 1/20 0.35
KDM4E B2RXH2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625399 0.74 POLB (0.42) POLBALDH1A1LMNAMEN1KMT2A
SCHEMBL8618660 0.74 POLB (0.42) ACP3POLBALDH1A1LMNAMEN1
SCHEMBL8624041 0.70 FDFT1 (0.45) POLBPPARGPPARAGAA
SCHEMBL8623400 0.70 FFAR1 (0.44) PPARGPPARAMAPTMEN1KMT2A
SCHEMBL4835745 0.69 POLB (0.50) ACP3POLBPPARGPPARAMEN1
SCHEMBL8619968 0.69 POLB (0.47) POLBALDH1A1LMNAMEN1KMT2A
SCHEMBL8623402 0.68 POLB (0.44) ACP3POLBPPARGPPARAALDH1A1
SCHEMBL1837398 0.68 POLB (0.64) POLBALDH1A1LMNAMAPTMEN1
SCHEMBL8625395 0.67 POLB (0.44) POLBMEN1KMT2AGAA
SCHEMBL9448849 0.67 POLB (0.58) POLBALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567841-A ANTICHOLESTEROL AGENT BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-22 US disclosed