Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947248 | 0.96 | ALDH1A1 (0.61) | ALDH1A1HPGDRARB | |
| SCHEMBL8947272 | 0.88 | RARB (0.47) | RARBTSHR | |
| SCHEMBL8947125 | 0.84 | L3MBTL1 (0.48) | ALDH1A1HPGDTSHR | |
| SCHEMBL8947141 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGD | |
| SCHEMBL9568775 | 0.82 | NPSR1 (0.50) | ALDH1A1HPGDTSHR | |
| SCHEMBL5966725 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDTSHR | |
| SCHEMBL8947299 | 0.77 | ALDH1A1 (0.66) | ALDH1A1HPGD | |
| SCHEMBL8947281 | 0.75 | ALDH1A1 (0.75) | ALDH1A1HPGD | |
| SCHEMBL8791414 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGD | |
| SCHEMBL9568716 | 0.74 | NPSR1 (0.46) | ALDH1A1RARBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35281-E | ANTIDIABETIC AGENTS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0388967-B1 | Aldose reductase inhibitor | WAKAMOTO PHARMA CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5055481-A | Alleviate diabetic complications | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0388967-A1 | Aldose reductase inhibitor | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1990-09-26 | — | — | EP | disclosed |