SCHEMBL8947370

SCHEMBL8947370

CCc1c(OP(=O)(Oc2ccc([N+](=O)[O-])c(CC)c2CC)Sc2ccc([N+](=O)[O-])c(CC)c2CC)ccc([N+](=O)[O-])c1CC

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.32
S1PR4 O95977 1/20 0.32
PDK1 Q15118 1/20 0.32
ALDH1A1 P00352 5/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
GAA P10253 2/20 0.31
HPGD P15428 2/20 0.31
MAPT P10636 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
ALPG P10696 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
USP7 Q93009 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2526894 0.82 CA1 (0.39) LMNAS1PR4ALDH1A1MEN1KMT2A
SCHEMBL1605003 0.80
SCHEMBL2526896 0.79 CA1 (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL14562946 0.79 PDK1 (0.35) LMNAPDK1ALDH1A1MEN1KMT2A
SCHEMBL2526898 0.79 CA1 (0.41) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL3182790 0.75 TDP1 (0.40) LMNAS1PR4PDK1ALDH1A1MEN1
SCHEMBL8947375 0.75 ALDH1A1 (0.35) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL8947379 0.75 ALDH1A1 (0.35) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL8214283 0.66 ALDH1A1 (0.49) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL8091152 0.66 PDK1 (0.42) LMNAPDK1ALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140228256-A1 METHOD AND KIT FOR CONSTRUCTING PLASMA DNA SEQUENCING LIBRARY BERRY GENOMICS CO., LTD. (CN) 2014-08-14 US claimed
US-10227587-B2 Method for constructing a plasma DNA sequencing library BERRY GENOMICS CO., LTD. (CN) 2019-03-12 US disclosed
US-20180142235-A1 METHOD FOR CONSTRUCTING A PLASMA DNA SEQUENCING LIBRARY ZHANG JIANGUANG (CN) 2018-05-24 US disclosed
CN-104694670-A LAMP (Loop-Mediated Isothermal Amplification) detection method of PRV (Porcine Rotavirus) inverse transcription and application UNIV NORTHEAST AGRICULTURAL 2015-06-10 CN disclosed
CN-104004839-A JAK2 genetic locus typing detection kit UNIV SOOCHOW 2014-08-27 CN disclosed
US-20140228256-A1 METHOD AND KIT FOR CONSTRUCTING PLASMA DNA SEQUENCING LIBRARY BERRY GENOMICS CO., LTD. (CN) 2014-08-14 US disclosed
CN-103255226-A Trichinella spiralis PCR-DHPLC detection primer, kit and detection method ZHENG QIUYUE 2013-08-21 CN disclosed
CN-103060461-A Specific primer and kit for detecting common food allergens TIANJIN BIOCHIP CO LTD 2013-04-24 CN disclosed
US-5562820-A Process for purifying water AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-10-08 US disclosed
US-5449467-A Process for purifying water DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1995-09-12 US disclosed