Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023997 | 0.95 | FPR2 (0.38) | FPR2HTR2CHTR2BHTR2A | |
| SCHEMBL8947428 | 0.93 | GABRA1 (0.39) | FPR2GABRA1GABRB2HTR2CHTR2B | |
| SCHEMBL13573422 | 0.92 | HTR2C (0.34) | FPR2HTR2CHTR2BHTR2A | |
| SCHEMBL8947434 | 0.92 | CNR2 (0.36) | FPR2GABRA1GABRB2HTR2C | |
| SCHEMBL18719251 | 0.92 | FPR2 (0.38) | FPR2GABRA1GABRB2 | |
| SCHEMBL8945926 | 0.91 | FPR2 (0.34) | FPR2GABRA1GABRB2FGFR1FGFR2 | |
| SCHEMBL8947437 | 0.91 | GABRA1 (0.36) | FPR2GABRA1GABRB2 | |
| SCHEMBL18718456 | 0.91 | FPR2 (0.36) | FPR2GABRA1GABRB2FGFR1FGFR2 | |
| SCHEMBL12024500 | 0.91 | FPR2 (0.32) | FPR2 | |
| SCHEMBL13579235 | 0.90 | FPR2 (0.36) | FPR2GABRA1GABRB2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |