Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301756 | 0.83 | TMEM97 (0.51) | PGRALDH1A1MEN1KMT2A | |
| SCHEMBL8662878 | 0.82 | CNR2 (0.50) | KDM4ECNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL1520170 | 0.79 | PGR (0.53) | KDM4ECNR2PGRRORARORC | |
| SCHEMBL6910089 | 0.78 | PGR (0.56) | KDM4ECNR2PGRRORARORC | |
| SCHEMBL27369455 | 0.78 | TSHR (0.57) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6421284 | 0.78 | CNR2 (0.57) | KDM4ECNR2PGRRORARORC | |
| SCHEMBL8119434 | 0.77 | ALDH1A1 (0.46) | KDM4ECNR2ALDH1A1HTTHPGD | |
| SCHEMBL25316072 | 0.76 | CNR2 (0.56) | KDM4ECNR2PGRRORARORC | |
| SCHEMBL8862370 | 0.76 | CNR2 (0.56) | KDM4ECNR2PGRRORARORC | |
| SCHEMBL30484777 | 0.76 | CNR2 (0.56) | KDM4ECNR2PGRRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552408-A | Benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-ht receptor antagonists | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1996-09-03 | — | — | US | disclosed |
| US-5358954-A | Antiserotonine agent, antiemetic, gastrointestinal disorders | BOEHRINGER INGELHEIM ITALIA (IT) | 1994-10-25 | — | — | US | disclosed |
| US-5223511-A | Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1993-06-29 | — | — | US | disclosed |