Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947835 | 0.86 | GAA (0.42) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL8716864 | 0.83 | GAA (0.45) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL8716997 | 0.83 | ACACB (0.45) | GAAACACBF2PLGPLAU | |
| SCHEMBL9163451 | 0.83 | ACACB (0.45) | GAAACACBF2PLGPLAU | |
| SCHEMBL7326146 | 0.80 | GAA (0.45) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL7395628 | 0.78 | GAA (0.48) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL7302360 | 0.78 | ACACB (0.45) | GAAACACBF2PLGPLAU | |
| SCHEMBL7327272 | 0.78 | GAA (0.42) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL7334523 | 0.78 | GAA (0.42) | GAAACACBF2MEN1ALDH1A1 | |
| SCHEMBL7332989 | 0.77 | F2 (0.47) | ACACBF2PLGPLATF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |