Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.74 |
| ▸ | TACR1 | P25103 | 8/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235622 | 0.88 | DPP4 (0.72) | DPP4TACR1KCNA5KCNH2 | |
| SCHEMBL8947993 | 0.86 | DPP4 (0.71) | DPP4TACR1KCNA5KCNH2 | |
| SCHEMBL8947899 | 0.85 | DPP4 (1.00) | DPP4TACR1KCNA5KCNH2 | |
| SCHEMBL2900202 | 0.83 | KCNA5 (0.73) | DPP4TACR1KCNA5KCNH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2901589 | 0.82 | DPP4 (0.71) | DPP4TACR1KCNA5KCNH2SMN1; SMN2 | |
| SCHEMBL10737608 | 0.81 | DPP4 (0.54) | DPP4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL8785517 | 0.81 | TACR1 (0.54) | DPP4TACR1KCNA5KCNH2KMT2A | |
| SCHEMBL8947966 | 0.79 | TACR1 (0.56) | DPP4TACR1KCNA5KCNH2KMT2A | |
| SCHEMBL8948070 | 0.78 | TACR1 (0.51) | DPP4TACR1KCNA5KCNH2KMT2A | |
| SCHEMBL4686848 | 0.75 | TACR1 (0.49) | DPP4TACR1KCNA5KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527811-A | CALCIUM- AND SUBSTANCE P RECEPTOR-ANTAGONIST ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-18 | — | — | US | claimed |