Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.47 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947812 | 0.85 | DPP4 (0.48) | TACR1DPP4KMT2AMEN1CRHBP | |
| SCHEMBL8947892 | 0.83 | DPP4 (0.64) | TACR1DPP4 | |
| SCHEMBL5236388 | 0.76 | DPP4 (0.70) | TACR1DPP4 | |
| SCHEMBL8834999 | 0.75 | TACR1 (0.44) | TACR1DPP4BRD4 | |
| SCHEMBL8948085 | 0.74 | TACR1 (0.52) | TACR1DPP4KMT2AMEN1CRHBP | |
| SCHEMBL8785208 | 0.74 | TACR1 (0.56) | TACR1 | |
| SCHEMBL8947993 | 0.74 | DPP4 (0.71) | TACR1DPP4 | |
| SCHEMBL8785003 | 0.73 | TACR1 (0.58) | TACR1DPP4KMT2AMEN1LMNA | |
| SCHEMBL9573685 | 0.72 | TACR1 (0.68) | TACR1DPP4KMT2AMEN1CRHBP | |
| SCHEMBL8785566 | 0.71 | TACR1 (0.56) | TACR1DPP4KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527811-A | CALCIUM- AND SUBSTANCE P RECEPTOR-ANTAGONIST ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-18 | — | — | US | claimed |