SCHEMBL8948201

SCHEMBL8948201

CC(=O)C=CC(C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948197 1.00 GLA (0.34) GLATDP1GABRPGABRDGABRA1
SCHEMBL14418868 0.78 GABRP (0.56) TDP1GABRPGABRDGABRA1GABRB1
SCHEMBL320740 0.77
SCHEMBL320739 0.77
SCHEMBL10680124 0.77
SCHEMBL1782527 0.76 GABRP (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL19199018 0.76 GABRP (0.37) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1782529 0.76 GABRP (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1783021 0.75 ALDH1A1 (0.33) GLATDP1ALDH1A1
SCHEMBL1783023 0.75 ALDH1A1 (0.33) GLATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484949-A Method for the synthesis of α β-unsaturated ketones NIPPON SODA CO., LTD. (JP) 1996-01-16 US disclosed
EP-0454867-A1 A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. NIPPON SODA CO (JP) 1991-11-06 EP disclosed
WO-1991007370-A1 A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES NIPPON SODA CO., LTD. (JP) 1991-05-30 WO disclosed