Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.62 |
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948162 | 0.90 | SIGMAR1 (0.69) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8948259 | 0.89 | SIGMAR1 (0.68) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759827 | 0.88 | SIGMAR1 (0.67) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9449985 | 0.84 | SIGMAR1 (0.72) | SIGMAR1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL9449447 | 0.83 | SIGMAR1 (0.71) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9449586 | 0.81 | SIGMAR1 (0.69) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759846 | 0.80 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9685601 | 0.80 | SIGMAR1 (0.60) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7760487 | 0.79 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9484568 | 0.79 | SIGMAR1 (0.62) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |