Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 8/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806337 | 0.78 | TGFBR1 (0.51) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL19806559 | 0.78 | DYRK1A (0.46) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL19806362 | 0.78 | TGFBR1 (0.47) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL15730182 | 0.76 | TGFBR1 (0.64) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL13874033 | 0.75 | TGFBR1 (0.48) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL20004304 | 0.75 | DYRK1A (0.51) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL17930295 | 0.74 | TGFBR1 (0.64) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL14826052 | 0.73 | DYRK1A (0.85) | TGFBR1DYRK1APDE4APDE3ACYP3A4 | |
| SCHEMBL19806480 | 0.72 | TGFBR1 (0.60) | TGFBR1DYRK1ACYP1A2METAP2 | |
| SCHEMBL10512208 | 0.71 | PDE3A (0.61) | TGFBR1DYRK1APDE4APDE3ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8183787-A | — | — | None | — | — | JP | disclosed |
| JP-H08183787-A | NEW PYRAZOLE DERIVATIVE | EISAI CO LTD | 1996-07-16 | — | — | JP | disclosed |