Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10231824 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11659540 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7153011 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7145829 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6917165 | 0.78 | HRH1 (0.47) | ALDH1A1MEN1KMT2ATSHRHRH1 | |
| SCHEMBL8905004 | 0.76 | MEN1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8905152 | 0.76 | MEN1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8905280 | 0.76 | MEN1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8948467 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL17470027 | 0.72 | MEN1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484902-A | HYDROCYANATION OF VINYL AROMATICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-16 | — | — | US | claimed |
| US-5175335-A | Reacting vinyl aryl compounds with a source of hydrocyanic acid in presence of nickle zero valent compound and nonracemic bidentate organophosphorus ligand | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-29 | — | — | US | claimed |