SCHEMBL6917165

SCHEMBL6917165

c1ccc(OC2CCC(Oc3ccccc3)O2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.47
SLC6A2 P23975 6/20 0.44
SLC6A3 Q01959 5/20 0.44
SLC6A4 P31645 4/20 0.44
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
CTSV O60911 2/20 0.38
CTSL P07711 2/20 0.38
CTSB P07858 2/20 0.38
CTSS P25774 2/20 0.38
CTSK P43235 2/20 0.38
CTSC P53634 2/20 0.38
LTA4H P09960 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CTSH P09668 1/20 0.38
CTSF Q9UBX1 1/20 0.38
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2574974 0.79 HRH1 (0.45) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL12589503 0.78 TDP1 (0.48) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL8948419 0.78 ALDH1A1 (0.47) HRH1TSHRTDP1ALDH1A1MEN1
Water SCHEMBL16039884 0.77 HRH1 (0.44) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL28379711 0.76 TDP1 (0.47) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL8516523 0.74 HRH1 (0.41) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL7157475 0.74 HRH1 (0.41) HRH1SLC6A2SLC6A3SLC6A4TDP1
SCHEMBL739210 0.73 DHFR (0.45) HRH1SLC6A2SLC6A3SLC6A4ALDH1A1
SCHEMBL29856 0.72 HRH1 (0.71) HRH1SLC6A2SLC6A3SLC6A4DDB1
SCHEMBL9473258 0.71 DDB1 (0.44) HRH1SLC6A2SLC6A3SLC6A4DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed