SCHEMBL8948557

SCHEMBL8948557

COc1ccc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c2c1C(=O)C(C)(C)O2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
BCAT1 P54687 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948738 0.86 AR (0.35)
SCHEMBL8948564 0.85 PGR (0.31)
SCHEMBL8948552 0.85 PGR (0.35)
SCHEMBL8948604 0.81 FFAR4 (0.34) BCAT1
SCHEMBL8948508 0.77 PGR (0.34)
SCHEMBL8948509 0.75
SCHEMBL8948787 0.74 PGR (0.33)
SCHEMBL8948727 0.74 AR (0.31)
SCHEMBL8948502 0.73
SCHEMBL8175929 0.73 BCAT1 (0.41) LMNATP53MAPTBCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed
WO-1995005079-A1 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS FMC CORPORATION (US) 1995-02-23 WO disclosed