Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948539 | 0.84 | MAPK1 (0.33) | TDP1MAPK1CYP3A4 | |
| SCHEMBL8948487 | 0.77 | MAPK1 (0.33) | TDP1MAPK1 | |
| SCHEMBL8948579 | 0.74 | ADORA2A (0.40) | TDP1ALDH1A1 | |
| SCHEMBL8948774 | 0.71 | CYP3A4 (0.35) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL8948723 | 0.70 | MAPK1 (0.35) | TDP1MAPK1CYP3A4 | |
| SCHEMBL8948553 | 0.64 | HTR6 (0.33) | CYP3A4ALDH1A1 | |
| SCHEMBL1969003 | 0.62 | TDP1 (0.47) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11475560 | 0.62 | CYP3A4 (0.55) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL4881789 | 0.62 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11849090 | 0.61 | CYP3A4 (0.46) | TDP1MAPK1CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |