Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742725 | 0.79 | CA1 (0.42) | TYMSPARP1MEN1KMT2ACYP3A4 | |
| SCHEMBL8652048 | 0.78 | TYMS (0.40) | TYMSMAPTTDP1CA1CA2 | |
| SCHEMBL5080247 | 0.78 | CA1 (0.42) | TYMSPARP1MEN1USP2KMT2A | |
| SCHEMBL8948742 | 0.78 | ALDH1A1 (0.33) | ADORA2ACYP3A4NPSR1TDP1CD44 | |
| SCHEMBL18089744 | 0.78 | ADORA2A (0.36) | ADORA2APTPRCPARP1MEN1USP2 | |
| SCHEMBL8948488 | 0.76 | PARP1 (0.38) | ADORA2APTPRCPARP1MEN1USP2 | |
| SCHEMBL8654461 | 0.75 | TYMS (0.38) | TYMS | |
| SCHEMBL10638208 | 0.75 | CA1 (0.46) | TYMSMEN1USP2KMT2ACYP3A4 | |
| SCHEMBL22851407 | 0.73 | GRK6 (0.41) | TYMSADORA2APTPRCPARP1MEN1 | |
| SCHEMBL8948584 | 0.73 | CA1 (0.50) | PTPRCMEN1KMT2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |