SCHEMBL8948614 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	ITGB3	P05106	14/20	0.56

▸	ITGA2B	P08514	14/20	0.56

▸	F10	P00742	13/20	0.56

▸	PRSS1	P07477	7/20	0.56

▸	PRSS2	P07478	7/20	0.56

▸	PRSS3	P35030	7/20	0.56

▸	F2	P00734	3/20	0.56

▸	SIGMAR1	Q99720	4/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8314782	1.00	ITGB3 (0.56)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8948719	1.00	ITGB3 (0.56)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8313192	0.88	ITGB3 (0.66)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8310900	0.88	F10 (0.52)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8948665	0.88	F10 (0.52)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8948621	0.88	F10 (0.52)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8317559	0.88	F10 (0.59)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8314784	0.87	SIGMAR1 (0.44)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL8311141	0.87	SIGMAR1 (0.44)	ITGB3ITGA2BF10PRSS1PRSS2
SCHEMBL27446990	0.87	ITGB3 (0.51)	ITGB3ITGA2BF10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5532255-A	Adhesion receptor antagonists	MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE)	1996-07-02	—	—	US	disclosed