Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963329 | 0.83 | ALDH1A1 (0.47) | TDP1ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8948698 | 0.82 | MAPT (0.42) | TDP1ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL18181623 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8948525 | 0.79 | ALDH1A1 (0.41) | TDP1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL10989535 | 0.76 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRMAPK1CYP1A2 | |
| SCHEMBL10320899 | 0.75 | SIRT6 (0.42) | TDP1ALDH1A1TSHRMAPK1CYP1A2 | |
| SCHEMBL8948519 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14444109 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11218997 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2963825 | 0.72 | MEN1 (0.50) | TDP1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |