Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659420 | 0.90 | ALDH1A1 (0.42) | PARP1ALDH1A1HSD17B10CYP3A4ALOX15 | |
| SCHEMBL2247062 | 0.78 | MAPT (0.49) | ALDH1A1HSD17B10CYP3A4TDP1ACHE | |
| SCHEMBL2962443 | 0.76 | MAPT (0.47) | ALDH1A1TDP1GPR35TSHRSMN1; SMN2 | |
| SCHEMBL2061341 | 0.75 | TDP1 (0.40) | ALDH1A1HSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL10580640 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL17802004 | 0.74 | KMT2A (0.41) | MAPTKMT2A | |
| SCHEMBL34462932 | 0.73 | RXRA (0.47) | PARP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7298106 | 0.72 | TDP1 (0.41) | ALDH1A1HSD17B10TDP1ACHEGPR35 | |
| SCHEMBL6634968 | 0.72 | PARP1 (0.51) | PARP1ALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL4096904 | 0.72 | MAPK1 (0.37) | PARP1ALDH1A1TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |
| EP-0079683-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4593109-A | Miticidal 1-(2-alkyl-2,3-dihydrobenzofuran-7-yl)-4-alkoxy-4-alkylsemicarbazides | SHELL OIL COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| US-4587259-A | Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters | SHELL OIL COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4577011-A | Miticidal 2-(2-alkyl-2,3-dihydrobenzofuran-7-yl)-N-alkoxy-N-alkyl-diazenecarboxamides | SHELL OIL COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4554283-A | Aphicidal 3-(2-alkyl-2,3-dihydrobenzofuran-7-yl)-5-(R,R1 -amino)-1,3,4-oxadiazol-2(3H)-ones | SHELL OIL COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4550121-A | AGRICULTURE | SHELL OIL COMPANY (US) | 1985-10-29 | — | — | US | disclosed |
| US-4514211-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0048040-B1 | 7-SUBSTITUTED 2,3-DIHYDROBENZOFURANS, THEIR PREPARATION AND THEIR USE AS PESTICIDES OR AS CHEMICAL INTERMEDIATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-08-29 | — | — | EP | disclosed |
| EP-0079683-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0048040-A1 | 7-Substituted 2,3-dihydrobenzofurans, their preparation and their use as pesticides or as chemical intermediates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-03-24 | — | — | EP | disclosed |
| US-4302592-A | Pesticidal 3-(2,3-dihydrobenzofuran-7-yl)-5-methoxy-1,3,4-oxadiazol-2(3H)-one | SHELL OIL COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-3963717-A | ANTIINFLAMMATORY, ANALGESIC | SANDOZ, INC. (US) | 1976-06-15 | — | — | US | disclosed |