Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766866 | 0.88 | TSHR (0.59) | TSHRNPC1MAPK1ALDH1A1LMNA | |
| SCHEMBL2654989 | 0.87 | TSHR (0.47) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL777261 | 0.86 | NPC1 (0.53) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29436920 | 0.86 | NPC1 (0.53) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16714063 | 0.85 | NPC1 (0.47) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28537033 | 0.83 | TSHR (0.78) | TSHRKMT2AMEN1MAPK1ALDH1A1 | |
| Propionic Acid SCHEMBL28600397 | 0.82 | TSHR (0.53) | TSHRKMT2AMEN1NPC1MAPK1 | |
| SCHEMBL29201681 | 0.82 | NPC1 (0.50) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10004127 | 0.82 | NPC1 (0.50) | TSHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL27501656 | 0.81 | TSHR (0.58) | TSHRKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573999-A | FUNGICIDES AND INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| US-5538940-A | FUNGICIDE, MITICIDE, INSECTICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |