Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766866 | 0.94 | TSHR (0.59) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL27554071 | 0.90 | ALDH1A1 (0.54) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL28537033 | 0.85 | TSHR (0.78) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL5662234 | 0.82 | TSHR (0.60) | TSHRALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL27770565 | 0.82 | TSHR (0.47) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL8948919 | 0.82 | TSHR (0.52) | TSHRALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL28754662 | 0.82 | SCN1A (0.60) | ALDH1A1L3MBTL1LMNAKDM4EMEN1 | |
| SCHEMBL3755789 | 0.81 | CES2 (0.50) | TSHRALDH1A1L3MBTL1TP53KMT2A | |
| SCHEMBL22462706 | 0.81 | TSHR (0.58) | TSHRALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL1534012 | 0.81 | ALDH1A1 (0.66) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916341-A | Pyrazole carboxamide compounds for the treatment of HBV | 组装生物科学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-113164493-A | Cyclic sulfonamide compounds for the treatment of HBV | 组装生物科学股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113166086-A | Cyclic sulfonamide compounds for the treatment of HBV | 组装生物科学股份有限公司 | 2021-07-23 | — | — | CN | disclosed |