Bromide

Bromide

SCHEMBL8948924

COC(=O)C=C(OC)c1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 3/20 0.34
LMNA P02545 1/20 0.34
CAPN1 P07384 2/20 0.34
HPGD P15428 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MIF P14174 1/20 0.33
SNCA P37840 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8948916 1.00 TSHR (0.36) TSHRKMT2AALDH1A1LMNACAPN1
Bromide SCHEMBL3558232 0.80 ALDH1A1 (0.53) TSHRKMT2AALDH1A1LMNAKDM4E
SCHEMBL7705763 0.77 ALDH1A1 (0.42) TSHRKMT2AALDH1A1LMNAHPGD
SCHEMBL7705766 0.77 ALDH1A1 (0.42) TSHRKMT2AALDH1A1LMNAHPGD
SCHEMBL8948983 0.77 TSHR (0.42) TSHRKMT2AALDH1A1LMNAHPGD
SCHEMBL8948976 0.77 TSHR (0.42) TSHRKMT2AALDH1A1LMNAHPGD
SCHEMBL10610585 0.77 TSHR (0.42) TSHRKMT2AALDH1A1LMNAHPGD
Bromide SCHEMBL9486470 0.75 KMT2A (0.35) KMT2AALDH1A1LMNAHPGDKDM4E
Bromide SCHEMBL9799361 0.75 NFE2L2 (0.41) KMT2AALDH1A1HPGDKDM4EHSD17B10
SCHEMBL10610893 0.74 TSHR (0.42) TSHRKMT2AALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5573999-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
US-5538940-A FUNGICIDE, MITICIDE, INSECTICIDE BASF AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed