SCHEMBL8948941

SCHEMBL8948941

Cc1cccc(OCC(=O)c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.61
MEN1 O00255 7/20 0.61
MAPT P10636 3/20 0.61
HTT P42858 1/20 0.57
ALDH1A1 P00352 2/20 0.56
GAA P10253 1/20 0.56
LMNA P02545 3/20 0.55
NPSR1 Q6W5P4 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
MAPK1 P28482 1/20 0.55
PLA2G1B P04054 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ATG4B Q9Y4P1 1/20 0.54
RECQL P46063 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3599787 0.87 NPC1 (0.58) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL9787375 0.86 GAA (0.54) KMT2AMEN1MAPTHTTALDH1A1
SCHEMBL9787148 0.84 MAOB (0.68) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL5839185 0.83 NR4A2 (0.66) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL30024728 0.83 LMNA (0.69) KMT2AMEN1MAPTHTTALDH1A1
SCHEMBL654293 0.83 LMNA (0.69) KMT2AMEN1MAPTHTTALDH1A1
SCHEMBL1068092 0.82 MAPT (0.69) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL11066998 0.82 KMT2A (0.62) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL6201913 0.81 NPC1 (0.64) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL3732530 0.81 NPC1 (0.69) KMT2AMEN1MAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5573999-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
US-5538940-A FUNGICIDE, MITICIDE, INSECTICIDE BASF AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0525516-B1 Derivatives of beta substituted cinnomic acid BASF AG (DE) 1995-09-27 EP disclosed
EP-0525516-A2 Derivatives of beta substituted cinnomic acid BASF Aktiengesellschaft (DE) 1993-02-03 EP disclosed
US-4153619-A MICROBIOCIDES RIKER LABORATORIES, INC. (US) 1979-05-08 US disclosed
US-4141990-A BACTERICIDES, FUNGICIDES RIKER LABORATORIES, INC. (US) 1979-02-27 US disclosed
US-4124704-A ANTIMICROBIAL RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed